Identification of novel Pax-6 splicing variants in squids and its relevance to camera eye development of the cephalopods
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Cephalopod eye evolution was modulated by the acquisition of Pax-6 splicing variants
Previous studies have reported that the developmental processes of vertebrate eyes are controlled by four Pax-6 splicing variants, each modulating different downstream genes, whereas those of insect eyes are controlled by duplicated Pax-6 genes. Cephalopods belong to the Protostomes but possess a camera-type eye similar to those in vertebrates. We examined Pax-6 variations in the squid and foun...
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تاریخ انتشار 2012